cell division — TargetMol Chemicals

Cat No.	Product Name	Synonyms	Targets
T8513	Spastazoline		Others
	Spastazoline is a potent and selective inhibitor of spastin(Human spastin with IC50 of 99 nM ).		Others
T6393	ARQ 621		Kinesin
	ARQ 621 is an allosteric, and selective Eg5 mitotic motor protein inhibitor. Phase 1.		Kinesin
T13818	Phytohemagglutinin	PHA-M	Apoptosis
	Phytohemagglutinin (PHA-M) is a lectin, isolated from the red kidney bean , induces apoptosis via increasing proapoptotic protein Bax and activating caspases-3. Anti-tumor activity		Apoptosis
T21970	ML-097		GTPase
	ML-097 (CID-2160985) is a pan activator of Ras-related GTPases		GTPase
T12642L	Simurosertib	TAK-931	CDK
	Simurosertib (TAK-931) is a selective and ATP-competitive cell division cycle 7 kinase inhibitor (IC50: <0.3 nM).		CDK
T21678	3MB-PP1		PLK
	3MB-PP1 is a bulky purine analog and a Polo-like kinase 1 (Plk1) inhibitor. In cells expressing analog-sensitive Plk1 alleles, 3MB-PP1 blocks mitotic progression and cell division arise by targeting Plk1. 3MB-PP1 specifi...		PLK
T0849	Pyrimethamine	Pirimecidan,RP 4753,Pirimetamin	DHFR , Antifolate , Parasite
	Pyrimethamine (Pirimecidan) is a competitive inhibitor of dihydrofolate reductase (DHFR), used as an antimalarial drug.		DHFR , Antifolate , Parasite
T8211	(±)-Decursinol	3',4'-dihydro-3'-hydroxy-Xanthyletin	Others , Antibacterial
	(±)-Decursinol (3',4'-dihydro-3'-hydroxy-Xanthyletin) is a natural product from Angelica gigas.		Others , Antibacterial
T22991	ML-099		Rho , Ras
	pan activator of Ras-related GTPases		Rho , Ras
T8586	Cicloprofen		Others
	cicloprofen is Cell division cycle 7-related protein kinase (human) inhibitor.		Others
T12642	(R)-Simurosertib	(R)-TAK-931	CDK
	(R)-Simurosertib ((R)-TAK-931) is an inhibitor of the ATP-competitive cell division cycle 7 (CDC7) kinase.		CDK
T3151	Brassinolide	Brassin lactone,24-Epibrassinolide	Apoptosis , Others
	Brassinolide (Brassin lactone) is a plant hormone isolated from rapeseed (Brassica napus) promoting stem elongation and cell division.		Apoptosis , Others
T2942	Psoralen	Ficusin,Furocoumarin,psoralene	Apoptosis , Influenza Virus , HIV Protease , DNA/RNA Synthesis
	Psoralen (Ficusin) is a furocoumarin that intercalates with DNA, inhibiting DNA synthesis and cell division.
T14304	Aphidicolin		Others
	Aphidicolin, an antibiotic derived from the mold Cephalosporium aphidicola, is a potent inhibitor of DNA (deoxyribonucleic acid) synthesis, effectively hindering the proliferation of herpes simplex virus[2]. It targets D...		Others
T15141	DM4	Ravtansine	Others , Microtubule Associated
	DM4 (Ravtansine) can be used in the preparation of antibody drug conjugate and it is an antitubulin agent. It can inhibit cell division.		Others , Microtubule Associated
T3256	MMAF	MonoMethyl auristatin F	Others , Microtubule Associated
	MMAF (MonoMethyl auristatin F), an antimitotic agent, inhibits cell division by blocking the polymerization of tubulin.		Others , Microtubule Associated
TMS2181	Trans-Zeatin	(E)-Zeatin	ERK , MEK , Endogenous Metabolite
	trans-Zeatin ((E)-Zeatin) is the member of the plant growth hormone family known as cytokinins, which regulate cell division, development, and nutrient processing.		ERK , MEK , Endogenous Metabolite
T3352	XL413		cholecystokinin , Casein Kinase , Pim , CDK
	XL-413 is an orally bioavailable cell division cycle 7 homolog (CDC7) kinase inhibitor with potential antineoplastic activity. XL-413 binds to and inhibits the activity of CDC7, which may result in the inhibition of DNA ...		cholecystokinin , Casein Kinase , Pim , CDK
T6437	Cefoperazone	Cefob,Medocef	Antibacterial , Antibiotic
	Cefoperazone (Medocef) binds to and inactivates penicillin-binding proteins (PBPs) located on the inner membrane of the bacterial cell wall. PBPs are enzymes involved in the terminal stages of assembling the bacterial ce...		Antibacterial , Antibiotic
T7132	(Rac)-Brassinazole	BRASSINAZOLE	P450
	(Rac)-Brassinazole are a class of phytohormones with essential roles in plant growth and development, including the promotion of stem elongation and cell division. Brassinazole is a triazole-type brassinosteroid biosynth...		P450